The daily serving is 4 capsules. To get the most benefit from the product, we recommend taking 2 with a morning meal and 2 capsules with an evening meal.

If you prefer you can open the capsules and add the powder to your food/drink.

Whey protein/Cow's milk is rich in alpha Lactalbumin which may improve absorption of Inositol and also the Calcium can improve Vitamin D absorption.

No we do not advise going above the recommended amount of 4 capsules a day.

One bottle lasts a month (30 days).

Your first bottle may last you longer as we recommend starting with 1 capsule twice a day so you can get used to the ingredients.

It usually takes 6 months to see the full effects of a supplement.

This depends on multiple factors including diet, whether you were deficient and also how consistent you are.

Supplements can impact on a molecular level and some of our cells live for over 120 days before being replaced.

A bottle can have a shelf life of up to 2 years.

you can see what the shelf life of your bottle is on the best before date found on the base of the bottle.

All doses in our product are within safe levels and do not exceed the maximum recommended amounts and so serious side effects are unlikely.

• Inositols can cause mild side effects in some people, like nausea, diarrhoea, headaches and dizziness. However starting at lower doses and easing into it will make this less likely.

The following side effects occur at very high doses - far higher than what is in our product:

• Chromium in high doses can cause low blood sugar, digestive symptoms and can affect organs like the kidneys, heart and nervous system.
• Zinc in very high doses can cause a metallic taste in the mouth as well kidney and stomach damage.
• Vitamin D in toxic doses can cause nausea, vomiting and weakness.

For this reason we do not recommend using multi-vitamins alongside our product.

We recommend speaking to your Doctor before starting any supplement especially if you're on medication, pregnant or breastfeeding.

This supplement contains doses based on adult requirements and therefore it is not suitable for those under the age of 18 years.

So much of PCOS is wrongly framed as being only a fertility issue. We wanted to create our Core product to be aimed at ALL of us with PCOS.

Many foods are fortified with folic acid. Taking extra folic acid is indicated primarily for those trying to conceive or those who have deficiency.

Many of us with PCOS may have a raised BMI (>30) and when trying to conceive will need a prescription-only dose of folic acid (5mg).

Click the studies to read them:

40:1 ratio Inositol

• Monastra, G., Unfer, V., Harrath, A.H. and Bizzarri, M., 2017. Combining treatment with myo-inositol and D-chiro-inositol (40: 1) is effective in restoring ovary function and metabolic balance in PCOS patients.Gynecological Endocrinology,33(1), pp.1-9.
• Kamenov, Z. and Gateva, A., 2020. Inositols in PCOS.Molecules,25(23), p.5566.
• Nordio, M., Basciani, S. and Camajani, E., 2019. The 40: 1 myo-inositol/D-chiro-inositol plasma ratio is able to restore ovulation in PCOS patients: comparison with other ratios.Eur Rev Med Pharmacol Sci,23(12), pp.5512-21.
• Benelli, E., Del Ghianda, S., Di Cosmo, C. and Tonacchera, M., 2016. A combined therapy with myo-inositol and D-chiro-inositol improves endocrine parameters and insulin resistance in PCOS young overweight women.International journal of endocrinology,2016.
• Minozzi, M., Nordio, M. and Pajalich, R., 2013. The combined therapy myo-inositol plus D-chiro-inositol, in a physiological ratio, reduces the cardiovascular risk by improving the lipid profile in PCOS patients.Age (years),26(5.1).

Vitamin D

• Morgante, G., Darino, I., Spanò, A., Luisi, S., Luddi, A., Piomboni, P., Governini, L. and De Leo, V., 2022. PCOS Physiopathology and Vitamin D Deficiency: Biological Insights and Perspectives for Treatment. Journal of Clinical Medicine, 11(15), p.4509.
• Krul-Poel, Y.H.M., Koenders, P.P., Steegers-Theunissen, R.P., Ten Boekel, E., Wee, M.T., Louwers, Y., Lips, P., Laven, J.S.E. and Simsek, S., 2018. Vitamin D and metabolic disturbances in polycystic ovary syndrome (PCOS): A cross-sectional study.PloS one,13(12), p.e0204748.
• Guo, S., Tal, R., Jiang, H., Yuan, T. and Liu, Y., 2020. Vitamin D supplementation ameliorates metabolic dysfunction in patients with PCOS: a systematicreview of RCTs and insight into the underlying mechanism.International journal of endocrinology,2020.

Zinc

• Guler, I., Himmetoglu, O., Turp, A., Erdem, A., Erdem, M., Onan, M.A., Taskiran, C., Taslipinar, M.Y. and Guner, H., 2014. Zinc and homocysteine levels in polycystic ovarian syndrome patients with insulin resistance. Biological trace element research, 158(3), pp.297-304.
• Nasiadek, M., Stragierowicz, J., Klimczak, M. and Kilanowicz, A., 2020. The role of zinc in selected female reproductive system disorders.Nutrients,12(8), p.2464.

Chromium

• Fazelian, S., Rouhani, M.H., Bank, S.S. and Amani, R., 2017. Chromium supplementation and polycystic ovary syndrome: A systematic review and meta-analysis.Journal of trace elements in medicine and biology,42, pp.92-96.
• Ashoush, S., Abou‐Gamrah, A., Bayoumy, H. and Othman, N., 2016. Chromium picolinate reduces insulin resistance in polycystic ovary syndrome: Randomized controlled trial.Journal of Obstetrics and Gynaecology Research,42(3), pp.279-285.
• Jamilian, M., Bahmani, F., Siavashani, M.A., Mazloomi, M., Asemi, Z. and Esmaillzadeh, A., 2016. The effects of chromium supplementation on endocrine profiles, biomarkers of inflammation, and oxidative stress in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial.Biological trace element research,172(1), pp.72-78.