Magnesium plays a role in wellbeing and hormonal health in particular:
Sleep
"Our study found a significant association between Magnesium depletion score (MDS) and sleep quality" (1)
PCOS and Pre-menstrual stress
"In clinical studies it was demonstrated that magnesium deficiency is associated with diseases and states such as dysmenorrhea, premenstrual syndrome (PMS), polycystic ovary syndrome (POS)" (2)
"magnesium supplementation could improve the markers for oxidative stress and metabolic disorders in PCOS patients"(3)
"The serum levels of HS-CRP, insulin and HOMA-IR were significantly improved by magnesium co-supplementation with other supplements." (3)
Benefits were expecially seen when taken with vitamin D and Zinc (found in our inositol infusion or prenatal formula).
Insulin resistance
Magnesium deficiency seems to worsen insulin resistance. (4)
Magnesium improved insulin resistance in those at risk of diabetes. (4)(5)
Gestational diabetes (in pregnancy)
Magnesium supplementation benefits glycemic control for gestational diabetes. (6)
Results from this meta-analysis prove the beneficial effects of magnesium supplementation in pregnant women with Gestational Diabetes Mellitus (GDM) (7)
Sources
(1) Luo, Xiaomin, et al. "Association between magnesium deficiency score and sleep quality in adults: A population-based cross-sectional study."Journal of Affective Disorders358 (2024): 105-112.
(2) Makatsariya A.D et al. Female magnesium deficiency and its management: review of current knowledge.Obstetrics, Gynecology and Reproduction. 2024;18(2):218-230.
(3) Li, Ruiyun, et al. "The effect of magnesium alone or its combination with other supplements on the markers of inflammation, OS and metabolism in women with polycystic ovarian syndrome (PCOS): A systematic review."Frontiers in Endocrinology13 (2022): 974042.
(4) Veronese N, Watutantrige-Fernando S, Luchini C, Solmi M, Sartore G, Sergi G, et al. Effect of magnesium supplementation on glucose metabolism in people with or at risk of diabetes: a systematic review and meta-analysis of double-blind randomized controlled trials.Eur J Clin Nutr(2016) 70(12):1354–9. doi: 10.1038/ejcn.2016.154
(5) Guerrero-Romero F, Jaquez-Chairez FO, Rodrjguez-Morán M. Magnesium in metabolic syndrome: a review based on randomized, double-blind clinical trials.Magnes Res(2016) 29(4):146–53. doi: 10.1684/mrh.2016.0404
(6) Tan, X., & Huang, Y. (2022). Magnesium supplementation for glycemic status in women with gestational diabetes: a systematic review and meta-analysis.Gynecological Endocrinology,38(3), 202-206.
(7) Qu, Q., Rong, R., & Yu, J. (2022). Effect of magnesium supplementation on pregnancy outcome in gestational diabetes mellitus patients: A meta‐analysis of randomized controlled trials.Food Science & Nutrition,10(10), 3193-3202.